Fish polyculture is an efficient and sustainable method of raising fish, which more and more fish farmers are practicing worldwide. This article discusses what fish polyculture is, how to select the ideal species of fish for polyculture, the benefits versus challenges, and a detailed case study considering tilapia and catfish. If you intend to do polyculture or are seeking to improve your fish polyculture system at the farm, then this comprehensive guide is all you will need.